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Specifications
- Antibody type:Primary
- Antigen name:Sentrin-specific Protease 6
- Clonality:Polyclonal
- Host:Goat
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:SENP6
- Conjugation:Unconjugated
- Size:100 µg
- Western blot:Yes
- Cross adsorption:No
- Antigen synonyms:RP1-134M13.1|FLJ11355|FLJ11887|SUSP1|SUMO1/sentrin specific protease 6|SUMO-1-specific protease|SSP1|KIAA0389|2810017C20Rik|KIAA0797|SUMO1/sentrin specific peptidase 6
- Storage buffer:TBS, pH 7.3, with 0.5% BSA and 0.02% Sodium azide
- Storage temperature:–20 °C, avoid freeze/thaw cycles
- Cat. no.:CAPIPA5-18881
- Supplier No.:PA5-18881
Specifications
About this item
This antibody is predicted to react with mouse and rat based on sequence homology. Ubiquitin-like molecules and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins . SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates .
Recommended Dilutions: Western Blot: 0.5-1.5 ug/ml
Type: Primary
Antigen: SENP6/SUSP1
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Goat
Isotype: none
Reactivity: Human