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Specifications
- Antibody type:Primary
- Antigen name:TNFR-associated protein 2
- Clonality:Polyclonal
- Host:Goat
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:TRAP2
- Conjugation:Unconjugated
- Size:100 µg
- Western blot:Yes
- Cross adsorption:No
- Antigen synonyms:TRAP2|Rpn1|P97|55.11 protein|26S proteasome non-ATPase regulatory subunit 2|non-ATPase|proteasome (prosome|26S proteasome regulatory subunit S2|S2|macropain) 26S subunit|proteasome 26S non-ATPase subunit 2|TNFR-associated protein 2|PSMD2|2|MGC14274|tumor necrosis factor receptor-associated protein 2|26S proteasome subunit p97
- Storage buffer:TBS, pH 7.3, with 0.5% BSA and 0.02% Sodium azide
- Storage temperature:–20 °C, avoid freeze/thaw cycles
- Cat. no.:CAPIPA5-18324
- Supplier No.:PA5-18324
Specifications
About this item
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.
Recommended Dilutions: Western Blot: 0.03-0.3 ug/ml
Type: Primary
Antigen: PSMD2 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 2)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Goat
Isotype: none
Reactivity: Human