To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Specifications
- Antibody type:Primary
- Antigen name:Centaurin beta 2
- Clonality:Polyclonal
- Host:Goat
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:CENTB2
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:100 µg
- Western blot:Yes
- Cross adsorption:No
- Antigen synonyms:ANK repeat and PH domains 2|KIAA0041|centaurin beta2|ArfGAP with coiled-coil|CNT-B2|Arf GAP with coiled coil|centaurin|CENTB2|ankyrin repeat and PH domains 2|beta 2|ACAP2
- Storage buffer:TBS, pH 7.3, with 0.5% BSA and 0.02% Sodium azide
- Storage temperature:–20 °C, avoid freeze/thaw cycles
- Tested applications:Immunohistochemistry
- Cat. no.:CAPIPA5-18209
- Supplier No.:PA5-18209
Specifications
About this item
This antibody is predicted to react with canine and porcine based on sequence homology. ACAP2 is a transport carrier belonging to the Centaurin family with three ANK repeats, an Arf-GAP domain, a BAR domain, and a PH domain. ACAP2, a GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) has robust constitutive ARF6 GAP activity, where the GAP activity is stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid but has little activity toward ARF1 and is known to control the return of ARF to the inactive GDB-bound shots. ACAP2, along with ACAP1, is targeted by phosphatidyl inositol (3, 4, 3) triphosphate inhibiting the formation of PDGF-induced dorsal membrane ruffles in NIH3T3 fibroblasts when overexpressed. ACAP2 is phosphorylated upon DNA damage, probably by ATM or ATR. Expression is wide-spread with the highest level in lung.
Immunohistochemistry: 5-10µg/ml, Western Blot: 0.3-1 µg/ml
Type: Primary
Antigen: ACAP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Goat
Isotype: IgG
Reactivity: Mouse, Rat, Human