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Specifications
- Antibody type:Primary
- Antigen name:Protein Tyrosine Phosphatase, Non-receptor Type 11
- Clonality:Polyclonal
- Gene ID:PTPN11/5781; Ptpn11/19247
- Host:Goat
- Isotype:IgG
- Reactivity:Human,Mouse
- Antigen symbol:PTPN11
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:100 µg
- Western blot:Yes
- Cross adsorption:No
- Antigen synonyms:SHP2|PTP2C|PTP-1D|SH-PTP3|METCDS|NS1|CFC|SH-PTP2|BPTP3|JMML
- Storage buffer:TBS, pH 7.3, with 0.5% BSA and 0.02% Sodium azide
- Storage temperature:–20 °C, avoid freeze/thaw cycles
- Tested applications:Immunohistochemistry (Paraffin)
- Cat. no.:CAPIPA5-17956
- Supplier No.:PA5-17956
Specifications
About this item
This antibody is predicted to react with bovine, porcine and rat based on sequence homology. The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Recommended Dilutions: Western Blot: 1-3 ug/ml, Immunohistochemistry (Paraffin): 2-4ug/ml
Type: Primary
Antigen: SHP2/PTPN11
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Goat
Isotype: none
Reactivity: Human