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Specifications
- Antibody type:Primary
- Antigen name:Ras-related protein Rab-8A
- Clonality:Polyclonal
- Host:Goat
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:RAB8A
- Conjugation:Unconjugated
- Size:100 µg
- Western blot:Yes
- Cross adsorption:No
- Antigen synonyms:mel transforming oncogene (derived from cell line NK14)|RAB8|RAB8A|mel transforming oncogene (derived from cell line NK14)- RAB8 homolog|ras-a|mel transforming oncogene (RAB8 homolog)|mel transforming oncogene|member RAS oncogene family|MEL
- Storage buffer:TBS, pH 7.3, with 0.5% BSA and 0.02% Sodium azide
- Storage temperature:–20 °C, avoid freeze/thaw cycles
- Cat. no.:CAPIPA5-18875
- Supplier No.:PA5-18875
Specifications
About this item
This antibody is predicted to react with bovine and canine based on sequence homology. The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13. 1.
Recommended Dilutions: Western Blot: 0.1-0.3 ug/ml
Type: Primary
Antigen: RAB8A (RAB8A, member RAS oncogene family)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Goat
Isotype: none
Reactivity: Human