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Specifications
- Antibody type:Primary
- Antigen name:DEXH (Asp-Glu-X-His) box Polypeptide 58
- Clonality:Polyclonal
- Host:Goat
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:LGP2
- Conjugation:Unconjugated
- Size:100 µg
- Western blot:Yes
- Cross adsorption:No
- Antigen synonyms:DEXH (Asp-Glu-X-His) box polypeptide 58 |RNA helicase LGP2 |D11LGP2 |DHX58|D11lgp2e |LGP2|ortholog of mouse D11lgp2
- Storage buffer:TBS, pH 7.3, with 0.5% BSA and 0.02% Sodium azide
- Storage temperature:–20 °C, avoid freeze/thaw cycles
- Cat. no.:CAPIPA5-18783
- Supplier No.:PA5-18783
Specifications
About this item
Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.
Western Blot: 0.3-1 ug/ml
Type: Primary
Antigen: DHX58
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Goat
Isotype: IgG
Reactivity: Human