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Specifications
- Antibody type:Primary
- Antigen name:Bcl-2-like protein 11
- Clonality:Polyclonal
- Host:Goat
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:BCL2L11
- Conjugation:Unconjugated
- Size:100 µg
- Western blot:Yes
- Cross adsorption:No
- Antigen synonyms:BAM|BOD|Bcl-2- Related Ovarian Death Gene|BCL2 interacting protein Bim
- Storage buffer:TBS, pH 7.3, with 0.5% BSA and 0.02% Sodium azide
- Storage temperature:–20 °C, avoid freeze/thaw cycles
- Cat. no.:CAPIPA5-18285
- Supplier No.:PA5-18285
Specifications
About this item
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 . It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X, and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor , as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
Western Blot: 0.5-2 ug/ml
Type: Primary
Antigen: Bim
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Goat
Isotype: IgG
Reactivity: Human