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Specifications
- Antibody type:Primary
- Antigen name:FK506 Binding Protein 12
- ChIP:Yes
- Clonality:Polyclonal
- Gel shift:Yes
- Host:Rabbit
- Isotype:IgG
- Neutralisation:Yes
- Reactivity:Human
- Antigen symbol:FKBP12
- Conjugation:Unconjugated
- ELISA:Yes
- Flow cytometry:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:400 µL
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:FKBP-12|FKBP1|EC 5.2.1.8|12 kDa FKBP|Rotamase|FKBP-1A|FKBP1A|PPIase FKBP1A|Peptidyl-prolyl cis-trans isomerase FKBP1A|FKBP12|Immunophilin FKBP12|FK506-binding protein 1A
- Storage buffer:PBS with 0.09% Sodium azide
- Molecular weight:11.95 kDa
- Storage temperature:Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at –20 °C
- Concentration:Lot-specific
- Immunogen:KLH conjugated synthetic peptide between 43-74 amino acids from the central region of human FKBP12
- Tested applications:Immunohistochemistry
- Purification:Ammonium sulfate precipitation, Size-exclusion - Dialysis
- Cat. no.:CAPIPA5-14852
- Supplier No.:PA514852
Specifications
About this item
This antibody is predicted to react with bovine, mouse, rat and rabbit based on sequence homology. FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry: 1:10-1:50
Type: Primary
Antigen: FKBP1A (FK506 binding protein 1A, 12kDa)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human