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Specifications
- Antibody type:Primary
- Antigen name:ARP1 Actin-related Protein 1 Homolog A, Centractin alpha
- ChIP:Yes
- Clonality:Polyclonal
- Gel shift:Yes
- Gene ID:ACVR1/90; Acvr1/11477
- Host:Rabbit
- Isotype:IgG
- Neutralisation:Yes
- Reactivity:Human,Mouse
- Antigen symbol:ACTR1A
- Conjugation:Unconjugated
- ELISA:Yes
- Flow cytometry:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:400 µL
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:centractin alpha (yeast)|centractin alpha|yeast) homolog A (centractin alpha)|FLJ52800|ARP1 actin-related protein 1 homolog A|CTRN1|FLJ52695|FLJ55002|actin-RPV|ARP1|ARP1 (actin-related protein 1|yeast homolog A|centrosome-associated actin homolog
- Storage buffer:PBS with 0.09% Sodium azide
- Molecular weight:57.15 kDa
- Storage temperature:Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at –20 °C
- Concentration:Lot-specific
- Immunogen:KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human Activin Receptor Type IA (ACVR1)
- Tested applications:Immunohistochemistry
- Purification:Ammonium sulfate precipitation, Size-exclusion - Dialysis
- Cat. no.:CAPIPA5-13881
- Supplier No.:PA513881
Specifications
About this item
This antibody is predicted to react with bovine based on sequence homology. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 is an activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors.
Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000
Type: Primary
Antigen: ACVR1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse