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Specifications
- Antibody type:Primary
- Antigen name:Thymidine Phosphorylase
- Clonality:Polyclonal
- Gene ID:1890
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:TYMP
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:100 µg
- Western blot:Yes
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:TP|MNGIE|PDECGF|ECGF1|hPD-ECGF|MEDPS1|ECGF|MTDPS1
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10388-136
- Supplier No.:BS-3809R
Specifications
About this item
In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500; IF(IHC-P): 1:50-200
Type: Primary
Antigen: TYMP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human