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Specifications
- Antibody type:Primary
- Antigen name:TROVE Domain Family, member 2
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:TROVE2
- Conjugation:Cy3®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:SS-A|TROVE2|TROVE domain family member 2|Ribonucleoprotein autoantigen SS A/Ro|RO60|SS A|SS-A/Ro|60 kDa ribonucleoprotein Ro|RoRNP|TROVE 2|SSA2|SSA 2|60 kDa SS A/Ro ribonucleoprotein|bA101E13.2|SSA|Gastric cancer multi drug resistance protein|Autoantigen Ro/SSA|TROVE2.|60 kDa Ro protein|RO 60|Sjogren syndrome antigen A2|RO60_HUMAN|Sjogren syndrome antigen A2 60kD ribonucleoprotein autoantigen SS A/Ro|Sjogren syndrome antigen A2 60kDa ribonucleoprotein autoantigen SS A/Ro|60 kDa SS-A/Ro ribonucleoprotein|60-KD|Sjoegren syndrome type A antigen|Ro 60 kDa autoantigen|Sjoegren syndrome antigen A2
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10462-066
- Supplier No.:BS-7116R-CY3
Specifications
About this item
Ro autoantigens are of clinical significance because directed against them are found in most patients with primary Sjqgren syndrome, subacute cutaneous lupus erythematosus (SLE), neonatal lupus erythematosus, ANA-negative lupus erythematosus, and systemic lupus erythematosus-like disease secondary to homozygous C2 or C4 complement deficiency (1). Ro/SSA is a ribonucleoprotein that binds to auto in 35 to 50% of patients with SLE and in up to 97% of patients with Sjqgren syndrome (2). The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules (2). Most anti-Ro/SSA-positive sera detect not only the main protein, but also a smaller Ro/SSA protein (2). The genes which encode the smaller and larger proteins map to human chromosomes 11p15.5 and 1q31, respectively (3?). La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with auto from patients with Sjé°ƒren syndrome and SLE (6).
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: TROVE2
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat