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Specifications
- Antibody type:Primary
- Antigen name:Phorbol-12-myristate-13-acetate-induced protein 1
- Clonality:Polyclonal
- Gene ID:5366
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:PMAIP1
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:Immediate-early-response protein APR|PMA-induced protein 1|NOXA|Protein Noxa|Phorbol-12-myristate-13-acetate-induced protein 1
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10461-114
- Supplier No.:BS-7074R
Specifications
About this item
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Recommended Dilutions: IHC-P: 1:100-500; IF(IHC-P): 1:50-200
Type: Primary
Antigen: PMAIP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat