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Specifications
- Antibody type:Primary
- Antigen name:Phospholipase A2, Group 6
- Clonality:Polyclonal
- Gene ID:8398
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:PLA2G6
- Conjugation:Alexa Fluor® 350
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:iPLA2|PARK14|CaI-PLA2|INAD1|PNPLA9|NBIA2|NBIA2A|iPLA2beta|NBIA2B|PLA2|IPLA2-VIA|GVI
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:660-710/806
- Purification:Purified by Protein A
- Cat. no.:10453-020
- Supplier No.:BS-6709R-A350
Specifications
About this item
Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: PLA2G6
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat