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Specifications
- Antibody type:Primary
- Antigen name:Rho GTPase Activating Protein 24
- Clonality:Polyclonal
- Gene ID:83478
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:ARHGAP24
- Conjugation:HRP (Horseradish Peroxidase)
- ImmunoChemistry:Yes
- Size:100 µL
- Western blot:Yes
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:RC-GAP72|RCGAP72|p73|FILGAP|p73RhoGAP
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:630-680/748
- Purification:Purified by Protein A
- Cat. no.:10423-528
- Supplier No.:BS-5785R-HRP
Specifications
About this item
Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500
Type: Primary
Antigen: ARHGAP24
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat