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Specifications
- Antibody type:Primary
- Antigen name:Protein Kinase C, Alpha
- Clonality:Polyclonal
- Gene ID:5578
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:PRKCA
- Conjugation:Cy7®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:PRKCE|Protein kinase C beta type|PKCG|PKCE|PRKCT|PRKCG|SDK1|PKC2|PKC-A|nPKC-zeta|nPKC-theta|Protein kinase C zeta type|Protein kinase C epsilon type|PRKACA|nPKC-epsilon|PKC-B|PRKCZ|Protein kinase C alpha type|nPKC-delta|PKC-alpha|PRKCA|PKC-beta|PRKCQ|PKCB|PKC-gamma|Protein kinase C theta type|Tyrosine-protein kinase PRKCD|Protein kinase C gamma type|Sphingosine-dependent protein kinase-1|Protein kinase C delta type|PRKCD|PRKCB|PKC zeta|PRKCB1|PKCA
- Modification:phospho-Ser657/Tyr658
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10417-868
- Supplier No.:BS-5573R-CY7
Specifications
About this item
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: PRKCA
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat