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Specifications
- Antibody type:Primary
- Antigen name:Amyloid Beta (A4) Precursor Protein-Binding, Family B, Member 1
- Clonality:Polyclonal
- Gene ID:322
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:APBB1
- Conjugation:Alexa Fluor® 555
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:amyloid beta A4 precursor protein-binding|APBB1|FE65|adaptor protein FE65a2|stat-like protein|MGC:9072|member 1|amyloid beta (A4) precursor protein-binding|RIR |family B|member 1 (Fe65)
- Modification:phospho-Ser175
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10409-906
- Supplier No.:BS-5165R-A555
Specifications
About this item
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: APBB1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat