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Specifications
- Antibody type:Primary
- Antigen name:Guanine Nucleotide Binding Protein (G Protein), Beta Polypeptide 3
- Clonality:Polyclonal
- Gene ID:2784
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:GNB3
- Conjugation:Cy7®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:My049|C20orf37|dJ794I6.3|HLC14-06-P
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Cat. no.:10390-418
- Supplier No.:BS-3943R-CY7
Specifications
About this item
G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: G protein beta 3/GNB3
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat