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Specifications
- Antibody type:Primary
- Antigen name:Integrin Alpha 2B
- Clonality:Polyclonal
- Gene ID:16399
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:ITGA2B
- Conjugation:HRP (Horseradish Peroxidase)
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:GP2B|GTA|platelet fibrinogen receptor|alpha subunit|CD41B|platelet membrane glycoprotein IIb|HPA3|integrin alpha-IIb|GPIIb|BDPLT2|CD41|GT|ITGA2B|platelet-specific antigen BAK|GPalpha IIb
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:370-420/1033
- Purification:Purified by Protein A
- Cat. no.:10343-214
- Supplier No.:BS-2636R-HRP
Specifications
About this item
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Recommended Dilutions: IHC-P: 1:100-500
Type: Primary
Antigen: ITGA2B
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat