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Specifications
- Antibody type:Primary
- Antigen name:Mitogen-Activated Protein Kinase 14
- Clonality:Polyclonal
- Gene ID:1432
- Host:Rabbit
- Isotype:IgG
- Reactivity:Goat,Human,Rat,Mouse
- Antigen symbol:MAPK14
- Conjugation:Cy5®
- ImmunoChemistry:Yes
- Size:100 µL
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:p38ALPHA|Mxi2|CSPB1|PRKM15|CSBP|CSBP2|EXIP|p38|RK|CSBP1|PRKM14|SAPK2A
- Modification:phospho-Thr180/Tyr182
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:160-200/360
- Purification:Purified by Protein A
- Cat. no.:10338-576
- Supplier No.:BS-2210R-CY5
Specifications
About this item
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: MAPK14
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Goat