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Specifications
- Antibody type:Primary
- Antigen name:integrin alpha 4
- Clonality:Monoclonal
- Clone:DATK32
- Gene ID:Q00651
- Host:Mouse
- Isotype:IgG2a kappa
- Reactivity:Mouse
- Antigen symbol:Itga4
- Conjugation:APC (Allophycocyanin)
- Flow cytometry:Yes
- Size:0.025 mg
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:Itga4
- Storage buffer:Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Cat. no.:10765-758
- Supplier No.:77-141
Specifications
About this item
The DATK32 monoclonal antibody specifically reacts with an epitoPE of the Mouse alpha-4-beta-7 integrin (LPAM-1). The two subunits of the LPAM-1 heterodimer are the 154 kDa alpha-4 and the 130 kDa beta-7. Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the alpha-4-beta-7 integrin heterodimer. alpha-4-beta-7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands (fibronectin, CD106, and MAdCAM-1). The interaction of DATK32 with the alpha-4-beta-7 induces the alpha-4-beta-7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion.
Type: Primary
Antigen: Itga4
Clonality: Monoclonal
Clone: DATK32
Conjugation: APC
Epitope:
Host: Mouse
Isotype: MouseIgG2a, kappa
Reactivity: Mouse