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Specifications
- Antibody type:Primary
- Antigen name:Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
- Clonality:Polyclonal
- Gene ID:Q99967
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:CITED2
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:N-Terminal
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:CITED2
- Storage buffer:CITED2 Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:30 kDa
- Storage temperature:CITED2 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:CITED2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CITED2. The immunogen is located within the first 50 amino acids of CITED2.
- Purification:CITED2 Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10751-778
- Supplier No.:7067_S
Specifications
About this item
CITED2 Antibody: CITED2 was initially identified as a potential transcriptional activator with significant homology to MSG1, a melanocyte-specific nuclear protein. CITED2 interacts with the histone acetyltransferase p300/CBP and acts as a coactivator to several DNA-binding transcription factors such as HIF-1 and AP-2. CITED2 also controls proliferation of mouse embryonic fibroblasts via the polycomb group genes Bmi-1 and Mel18 and the tumor suppressor Ink4a/Arf. CITED2 has also been found to be an essential regulator of adult hematopoietic stem cells (HSCs), with conditional deletion of CITED2 in the adult mouse resulting in the loss of HSCs, multilineage bone marrow failure and increased lethality.
Type: Primary
Antigen: CITED2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat