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Specifications
- Antibody type:Primary
- Antigen name:thymocyte selection-associated high mobility group box protein TOX
- Clonality:Polyclonal
- Gene ID:O94900
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:TOX
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:N-Terminal
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:TOX
- Storage buffer:TOX Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:58 kDa
- Storage temperature:TOX antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:TOX antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human TOX. The immunogen is located within amino acids 130 - 180 of TOX.
- Purification:TOX Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10751-714
- Supplier No.:6987_S
Specifications
About this item
TOX Antibody: TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
Type: Primary
Antigen: TOX
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human