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Specifications
- Antibody type:Primary
- Antigen name:actin filament associated protein 1
- Clonality:Polyclonal
- Gene ID:Q8N556
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Mouse
- Antigen symbol:AFAP1
- Conjugation:Unconjugated
- ELISA:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:near the N-Terminus
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:AFAP1
- Storage buffer:AFAP1 Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage temperature:AFAP1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:AFAP1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human AFAP1. The immunogen is located within amino acids 30 - 80 of AFAP1.
- Purification:AFAP1 Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10751-466
- Supplier No.:6557_S
Specifications
About this item
AFAP1 Antibody: The actin filament-associated protein AFAP1 (AFAP-110) is an actin cross-linking protein first identified as a substrate of the viral oncogene v-Src. AFAP1 has a fundamental role in actin cytoskeleton arrangement. It contains a carboxyterminal actin-binding domain that directly binds to F-actin and serves as an adaptor protein in the regulation of SRC and PKC signal transduction by several functional domains, including 2 pleckstrin homology (PH) domains, a Src homology 3-binding (SH3-binding) motif, and several SH2-binding motifs. It is overexpressed in prostate carcinoma and contributes to tumor growth by regulating cell-matrix adhesions and migration in the cancer cells. AFAP1 represent a possible therapeutic target for controlling tumorigenesis and metastasis.
Type: Primary
Antigen: AFAP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse