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Specifications
- Antibody type:Primary
- Antigen name:tectonic family member 1
- Clonality:Polyclonal
- Gene ID:Q2MV58
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Mouse
- Antigen symbol:TCTN1
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:N-Terminal
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:TCTN1
- Storage buffer:TCTN1 Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage temperature:TCTN1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:TCTN1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human TCTN1. The immunogen is located within amino acids 30 - 80 of TCTN1.
- Purification:TCTN1 Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10751-008
- Supplier No.:5833_S
Specifications
About this item
TCTN1 Antibody: TCTN1 is the founding member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. During embryonic development, TCTN1 is expressed in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
Type: Primary
Antigen: TCTN1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse