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Specifications
- Antibody type:Primary
- Antigen name:NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2
- Clonality:Polyclonal
- Gene ID:Q8N183
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:NDUFAF2
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:NDUFAF2
- Storage buffer:Mimitin Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage temperature:Mimitin antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:Mimitin antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Mimitin. The immunogen is located within the last 50 amino acids of Mimitin.
- Purification:Mimitin Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10750-690
- Supplier No.:5445_S
Specifications
About this item
Mimitin Antibody: Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kappa B-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.
Type: Primary
Antigen: NDUFAF2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human