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Specifications
- Antibody type:Primary
- Antigen name:solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
- Clonality:Polyclonal
- Gene ID:Q9NTN3
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:SLC35D1
- Conjugation:Unconjugated
- ELISA:Yes
- Size:0.02 mg
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:SLC35D1
- Storage buffer:Slc35D1 Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage temperature:Slc35D1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:Slc35D1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of the human Slc35D1. The immunogen is located within the last 50 amino acids of Slc35D1.
- Tested applications:Immunocytochemistry
- Purification:Slc35D1 Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10750-176
- Supplier No.:4607_S
Specifications
About this item
Slc35D1 Antibody: The solute carrier family Slc35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident Slc family member Slc35D1 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. These molecules can serve as substrates for chondroitin sulfate biosynthesis and mice lacking the Slc35D1 gene developed a lethal form of skeletal dysplasia with severe shortening of limbs and facial structures. Examination of epiphyseal cartilage in these mice revealed a decreased proliferating zone with round chrondrocytes, scarce matrices, and reduced proteoglycan aggregates. Loss of function mutations in human Slc35D1 cause Schneckenbecken dysplasia, a severe skeletal dysplasia.
Type: Primary
Antigen: SLC35D1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human