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Specifications
- Antibody type:Primary
- Antigen name:nerve growth factor receptor (TNFR superfamily, member 16)
- Clonality:Polyclonal
- Gene ID:P08138
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Mouse
- Antigen symbol:NGFR
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:NGFR
- Storage buffer:NGFR Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage temperature:NGFR antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:NGFR antibody was raised against purified recombinant human NGFR.
- Tested applications:Immunocytochemistry
- Purification:NGFR Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10749-710
- Supplier No.:3593_S
Specifications
About this item
NGFR Antibody: The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-kappa B and various mitogen-activated protein kinases. Nerve growth factor receptor (NGFR) was one of the earliest characterized members of this family. Also known as the low-affinity receptor p75NTR, this receptor is involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination. Its ligands include NGF, brain-derived neurotrophic factor (BDNF), NT3, and NT4. NGFR can also associate with other NGF receptors such as Trk through the cytosolic and transmembrane domains and thus can function as a co-receptor that refines Trk affinity and specificity for neurotrophins. Finally, upon binding of various neurotrophins, NGFR associates with tumor necrosis factor receptor-6 (TRAF6), suggesting that it can potentially function as a signal transducer for NGF signals through NGFR.
Type: Primary
Antigen: NGFR
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse