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Specifications
- Antibody type:Primary
- Antigen name:tripartite motif-containing 5
- Clonality:Polyclonal
- Gene ID:Q0PF16
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:TRIM5
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:TRIM5
- Storage buffer:TRIM5 alpha Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Predicted: 54 kDa Observed: 55 kDa
- Storage temperature:TRIM5 alpha antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:TRIM5 alpha antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of rhesus monkey TRIM5 alpha. The immunogen is located within the last 50 amino acids of TRIM5 alpha.
- Purification:TRIM5 alpha Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10749-594
- Supplier No.:3249_S
Specifications
About this item
TRIM5 alpha Antibody: TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. Expression of TRIM5alpha variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. All TRIM5alpha variants could inhibit at least two different retroviruses, but not from those viruses isolated from the same species, suggesting that TRIM5alpha acts as a natural barrier to cross-species retrovirus transmission.
Type: Primary
Antigen: TRIM5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human