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Specifications
- Antibody type:Primary
- Antigen name:tripartite motif-containing 5
- Clonality:Polyclonal
- Gene ID:Q9C035
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:TRIM5
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:C-Terminal
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:TRIM5
- Storage buffer:TRIM5 delta Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Predicted: 36 kDa Observed: 33 kDa
- Storage temperature:TRIM5 delta antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:TRIM5 delta antibody was raised against a synthetic peptide corresponding to 13 amino acids near the carboxy terminus of human TRIM5 delta. The immunogen is located within the last 50 amino acids of TRIM5 delta.
- Purification:TRIM5 delta Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10749-590
- Supplier No.:3241_S
Specifications
About this item
TRIM5 delta Antibody: TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has five alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. Expression of TRIM5alpha variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. The TRIM5delta isoform has been shown to colocalize with the topoisomerase I-interacting proteins BTBD1 and BTBD2 in punctate or elongated cytoplasmic bodies in several mouse and human cells where it appears to serve as a scaffold for the assembly of endogenous BTBD proteins. TRIM5delta also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner.
Type: Primary
Antigen: TRIM5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human