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Specifications
- Antibody type:Primary
- Antigen name:tripartite motif-containing 5
- Clonality:Polyclonal
- Gene ID:Q9C035
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:TRIM5
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:C-Terminal
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:TRIM5
- Storage buffer:TRIM5 gamma Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage temperature:TRIM5 gamma antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:TRIM5 gamma antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of human TRIM5 gamma. The immunogen is located within the last 50 amino acids of TRIM5 gamma.
- Purification:TRIM5 gamma Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10749-588
- Supplier No.:3239_S
Specifications
About this item
TRIM5 gamma Antibody: TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has five alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. While a function has not yet been assigned to TRIM5gamma, it is known that expression of TRIM5alpha variants from humans, rhesus monkeys, and African green monkeys enable resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. Furthermore, the TRIM5delta isoform appears to serve as a scaffold for the assembly of endogenous BTBD1 and BTBD2 proteins and also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner.
Type: Primary
Antigen: TRIM5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human