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Specifications
- Antibody type:Primary
- Antigen name:interleukin 27 receptor, alpha
- Clonality:Polyclonal
- Gene ID:Q6UWB1
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:IL27RA
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:near the C-Terminus
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:IL27RA
- Storage buffer:TCCR Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:70 kDa
- Storage temperature:TCCR antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Shipping temperature:4 °C
- Immunogen:TCCR antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human TCCR precursor. The sequence is identical to that of mouse TCCR. The immunogen is located within the last 50 amino acids of TCCR.
- Purification:TCCR Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10749-466
- Supplier No.:2483_S
Specifications
About this item
TCCR Antibody: Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.
Type: Primary
Antigen: IL27RA
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human