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Specifications
- Antibody type:Primary
- Antigen name:tumor necrosis factor receptor superfamily, member 21
- Clonality:Polyclonal
- Gene ID:O75509
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:TNFRSF21
- Conjugation:Unconjugated
- ELISA:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:N-Terminal
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:TNFRSF21
- Storage buffer:DR6 Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:68 kDa
- Storage temperature:DR6 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Shipping temperature:4 °C
- Immunogen:DR6 antibody was raised against a 15 amino acid peptide near the amino terminus of human DR6. The immunogen is located within amino acids 30 - 80 of DR6.
- Purification:DR6 Antibody is Antibody is DEAE purified.
- Cat. no.:10749-332
- Supplier No.:2157_S
Specifications
About this item
DR6 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa B and JNK. DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified.
Type: Primary
Antigen: TNFRSF21
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human