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Specifications
- Antibody type:Primary
- Antigen name:oligodendrocyte lineage transcription factor 2
- Clonality:Polyclonal
- Gene ID:Q13516
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:OLIG2
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:near the N-Terminus
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:OLIG2
- Storage buffer:OLIG2 Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Predicted: 36 kDa Observed: 37 kDa
- Storage temperature:OLIG2 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:OLIG2 antibody was raised against a 15 amino acid peptide near the amino terminus of human OLIG2. The immunogen is located within amino acids 80 - 130 of OLIG2.
- Purification:OLIG2 antibody is affinity chromatography purified via peptide column.
- Cat. no.:10748-892
- Supplier No.:7743_S
Specifications
About this item
The oligodendrocyte transcription factors 1 and 2 (OLIG1 and OLIG2, respectively) make up part of basic helix-loop-helix (bHLH) family of transcription factors that are specifically expressed in zones of the neuroepithelium from which oligodendrocyte precursors emerge. Both OLIG1 and OLIG2 genes are downstream targets of Sonic hedgehog and are expressed exclusively in the central nervous system. OLIG2 is first observed in the ventral most p3 progenitor domain of the ventral neural tube while OLIG1 is first expressed in the dorsal portion of the p3 domain. Mice overexpressing OLIG2 exhibit impaired potassium channel expression in neural progenitors and proliferation of these cells similar to that seen in Down Syndrome, suggesting that OLIG2 may play a role in this pathology.
Type: Primary
Antigen: OLIG2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat