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Specifications
- Antibody type:Primary
- Antigen name:acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
- Clonality:Polyclonal
- Gene ID:P39687
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:ANP32A
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:0.02 mg
- Western blot:Yes
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:ANP32A
- Storage buffer:PHAP Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage temperature:PHAP antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:PHAP antibody was raised with a synthetic peptide corresponding to amino acids at amino terminus of human PHAP. The immunogen is located within the first 50 amino acids of PHAP.
- Purification:PHAP Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10748-294
- Supplier No.:3149_S
Specifications
About this item
PHAP Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
Type: Primary
Antigen: ANP32A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat