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Specifications
- Antibody type:Primary
- Antigen name:mitogen-activated protein kinase kinase kinase 14
- Clonality:Polyclonal
- Gene ID:Q99558
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:MAP3K14
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoFluorescence:Yes
- Size:0.02 mg
- Western blot:Yes
- Epitope:near the C-Terminus
- Cross adsorption:No
- Form:Liquid
- Antigen synonyms:MAP3K14
- Storage buffer:NIK Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Predicted: 104 kDa
- Storage temperature:NIK antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Shipping temperature:4 °C
- Immunogen:NIK antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NIK. The immunogen is located within the last 50 amino acids of NIK.
- Tested applications:Immunocytochemistry
- Purification:NIK Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10748-224
- Supplier No.:1129_S
Specifications
About this item
NIK Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha , LPS and mitogens. A serine/threonine protein kinase which mediates NF-kappa B activation by IL-1, TNFalpha and CD95 was identified recently and designated NIK (for NF-kappa B inducing kinase). NIK is an activator of Ikappa B kinase alpha and beta (IKKalpha and IKKbeta ;). Therefore, NIK is a key molecule in the NF-kappa B signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.
Type: Primary
Antigen: MAP3K14
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human