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Specifications
- Protein/peptide type:Recombinant
- Source:HEK293 cells
- Species:Human
- Size:0.1 mg
- Tag sequence:C-Fc Tag
- Biological activity:Measured by its ability to bind biotinylated Neu5Ac alpha 2-6GalNAc alpha (sialyl-Tn).
- Protein synonyms:CDw327|CD33L|SIGLEC6|CD327|OBBP1|CD33L1|OB-BP1
- Protein/peptide name:Siglec6
- Purity:>92% as determined by SDS-PAGE.
- Molecular weight:60.3 kDa
- Formulation:Lyophilized, 50 mM tris, 100 mM glycine, pH7.5
- Tested applications:Western Blot
- Cat. no.:10798-368
- Supplier No.:96-692
Specifications
About this item
Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.