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Specifications
- Protein/peptide type:Recombinant
- Source:HEK293 cells
- Species:Human
- Size:0.1 mg
- Tag sequence:His Tag
- Protein synonyms:PVRL1|CD111|OFC7|PVRR|PVRR1|PRR|HVEC|ED4|CLPED1|HIgR|Nectin-1|SK-12|PRR1
- Protein/peptide name:Nectin 1
- Purity:>95% as determined by SDS-PAGE.
- Molecular weight:34.8 kDa
- Formulation:Lyophilized, PBS, pH7.4
- Tested applications:Western Blot
- Cat. no.:10797-852
- Supplier No.:96-642
Specifications
About this item
Poliovirus receptor-related protein 1 (PVRL1) is also known as Herpes virus entry mediator C (HveC), Herpesvirus Ig-like receptor (HIgR), Nectin-1, CD antigen CD111, PVRL1 / Nectin-1 / CD111 belongs to the nectin family. PVRL1 / Nectin-1 is a membrane protein with three extracellular immunoglobulin domains, a single transmembrane helix and a cytoplasmic tail. The protein can mediate Ca2+-independent cellular adhesion further characterizing it as IgSF cell adhesion molecule (IgSF CAM). PVRL1 is adhesion molecule found in a wide range of tissues. PVRL1 / Nectin-1 promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4.