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Specifications
- Antibody type:Primary
- Antigen name:Connexin 40
- Clonality:Polyclonal
- Host:Sheep
- Isotype:IgG
- Reactivity:Rat
- Antigen symbol:CX40
- Conjugation:Unconjugated
- ImmunoFluorescence:Yes
- Size:100 µL
- Western blot:Yes
- Epitope:253-269 aa
- Cross adsorption:No
- Format:Lyophilized
- Antigen synonyms:Gja5|GJA5|Cxn-40|gap junction alpha-5 protein|ATFB11|Gap junction alpha-5 protein|Cx40|CX40
- Immunogen:A synthetic peptide (SLVQGLTP PPDFNQCLK) as part of rat Connexin-40 protein (aa: 253-269) conjugated to diphtheria toxoid has been used as the immunogen.
- Cat. no.:10782-666
- Supplier No.:S-063-100
Specifications
About this item
FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low molecular weight diffuse from one cell to a neighboring cell. SUBUNIT: A connexon is composed of a hexamer of connexins. SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein. TISSUE SPECIFICITY: Highly expressed in lung. SIMILARITY: Belongs to the connexin family. Alpha-type (group II) subfamily.
Western blotting of cell membranes of COS cells transiently transfected with cDNA encoding Connexin-40 shows two bands of molecular weight 38 and 40 kDa which are abolished by preincubation with the immunising peptide. No such bands are detected in western blots of membranes from non-transfected cells or cells transfected with cDNA encoding Connexin-37, Connexin-43 or Connexin-45.
Application Information:
Immunofluorescence, Western blot. A dilution of 1:10,000 to 1: 50,000 is recommended for these applications. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: CX40
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: 253-269 aa
Host: Sheep
Isotype:
Reactivity: