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Specifications
- Antibody type:Primary
- Antigen name:AP1 Complex Subunit gamma-1
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat
- Antigen symbol:AP1G1
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:100 µL
- Western blot:Yes
- Epitope:amino acids 5-24 of Human AP-1
- Cross adsorption:No
- Format:Lyophilized
- Antigen synonyms:CLAPG1|ADTG|AP-1 complex subunit gamma-1
- Immunogen:A synthetic peptide (IRLRELIRTIRTARTQAEER) corresponding to the amino acids 5-24 of human AP-1 complex subunit gamma-1 conjugated to diphtheria toxin has been used as the immunogen. The peptide is homologous with the corresponding sequence derived from AP-1 complex subunit gamma-1 protein in mouse, rat, dog and zebra fish.
- Cat. no.:10782-542
- Supplier No.:R-166-100
Specifications
About this item
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans Golgi network to lysosomes. Together with medium and small subunits, adaptins form a heterotetrameric complex called an adaptor whose role is to promote the formation of clathrin-coated pits and vesicles and to recognise sorting signals within the cytosolic tails of transmembrane cargo molecules. Gamma-adaptin protein belongs to the adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network and/or endosomes. SUBCELLULAR LOCATION: Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane.
This antibody has been shown to be specific for AP-1
Application Information:
IHC, WB. This antibody works in immunohistochemistry on frozen or wax embedded tissue. Antigen retrieval has been used in testing but may not be necessary. Typical working dilutions are 1: 200 to 1: 2000 depending on tissue and detection method. For western blotting, 1: 1000 to 1: 4000 is recommended depending on detection method. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: AP1G1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: amino acids 5-24 of Human AP-1
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat