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Specifications
- Antibody type:Primary
- Antigen name:GDNF Family Receptor Alpha 2
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Rat
- Antigen symbol:GFRA2
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:100 µL
- Western blot:Yes
- Epitope:Human GFR alpha-2 protein (aa: 376-390)
- Cross adsorption:No
- Format:Lyophilized
- Antigen synonyms:GDNF family receptor alpha-2|NTNRA|RETL2|GDNFRB|GDNF receptor alpha-2|GDNF receptor beta|TRNR2|GFR alpha 2|NRTNR-ALPHA
- Immunogen:A synthetic peptide (PRVEKTPSLPDDLSD) as a part of human GFR alpha-2 protein (aa: 376-390) conjugated to KLH.
- Cat. no.:10782-362
- Supplier No.:R-067-100
Specifications
About this item
FUNCTION: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. SUBCELLULAR LOCATION: Cell membrane; lipid-anchor; GPI-anchor (By similarity). ALTERNATIVE PRODUCTS: 2 named isoforms produced by alternative splicing.
Western blot analysis indicates a high level of specificity to GFR alpha-2 for this antiserum.
Application Information:
IHC, WB. A dilution of 1:500 to 1:1000 is recommended for both applications. This antibody stains beautifully the large neurons in the rat DRG. This antibody also is ideal for WB analysis of rat DRG and brain homogenate. The optimal dilution should be determined by the end user, but a dilution of 1 in 500 is recommended for initial testing. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: GFR alpha-2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Human GFR alpha-2 protein (aa: 376-390)
Host: Rabbit
Isotype: IgG
Reactivity: Rat