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Specifications
- Antibody type:Primary
- Antigen name:C-Reactive Protein
- Clonality:Polyclonal
- Host:Chicken
- Isotype:IgY
- Reactivity:Mouse
- Antigen symbol:CRP
- Conjugation:Unconjugated
- ELISA:Yes
- Size:100 µL
- Western blot:Yes
- Epitope:C-Terminal (210-225 aa)
- Cross adsorption:No
- Format:Liquid
- Antigen synonyms:CRP1|MGC149895|C-reactive protein|pentraxin 1|CRP|D1S181E|RP11-419N10.4|CSRP|CYRP|MGC88244|PTX1
- Immunogen:A peptide from the C-terminus of mouse C-reactive protein (210-225 aa).
- Cat. no.:10781-922
- Supplier No.:C-1511-100
Specifications
About this item
C-reactive protein has several roles associated with host defence such as; promoting agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. COFACTOR: Binds 2 calcium ions per subunit. C-reactive protein exists as a homopentamer. There are 2 alternatively spliced isoforms. C-reactive protein is found in plasma and its concentration increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6.
The antibody detects mouse C-reactive protein in western blots by virtue of its epitope being the C-terminal peptide of the protein, amino acids 210-225. Because of homology, reactivity with C-terminal protein from other species is expected. The antibody also reacts in ELISA with mouse C-reactive protein
Application Information:
ELISA and WB. Suggested dilution of 1:2,000-1:5,000. Biosensis recommends that the optimal working dilution should be determined by the end user.
Type: Primary
Antigen: CRP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal (210-225 aa)
Host: Chicken
Isotype:
Reactivity: