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Specifications
- Antibody type:Primary
- Antigen name:Melanoma Cell Adhesion Molecule
- Clonality:Monoclonal
- Clone:4D8A9
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Antigen symbol:MCAM
- Conjugation:Unconjugated
- ELISA:Yes
- Flow cytometry:Yes
- ImmunoChemistry:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:EndoCAM|Mel-CAM|Muc 18|CD146
- Storage buffer:PBS with 0.0.2% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Fusion Protein
- Purification:Protein G Purification
- Cat. no.:10084-272
- Supplier No.:66153-1-IG
Specifications
About this item
CD146, also known as melanoma cell adhesion molecule (MCAM) or MUC18, originally identified as a biomarker of melanoma progression, is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally, it consists of five Ig domains, a transmembrane domain, and a cytoplasmic region. In normal adult tissue, CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis, and has been used as marker of circulating endothelium cells (CECs) .
Western Blot:A375 Cells, 1:500-1:5000; IHC: Human Placenta Tissue, 1:20-1:200; FC: HeLa Cells, N/A
Type: Primary
Antigen: MCAM
Clonality: Monoclonal
Clone: 4D8A9
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human