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Specifications
- Antibody type:Primary
- Antigen name:Villin 1
- Clonality:Monoclonal
- Clone:2B7B9
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human,Mouse
- Antigen symbol:VIL1
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:VIL
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Fusion Protein
- Purification:Protein G Purification
- Supplier No.:66096-1-IG
Specifications
About this item
Villin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
Western Blot: Human Kidney, 1:500-1:5000; IHC: Human small intestine Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100; IP: Mouse Kidney Tissue, 1:500-1:5000
Type: Primary
Antigen: VIL1
Clonality: Monoclonal
Clone: 2B7B9
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse