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Specifications
- Antibody type:Primary
- Antigen name:RNA Binding Motif Protein 15
- Clonality:Monoclonal
- Clone:4A1A4
- Host:Mouse
- Isotype:IgG2a
- Reactivity:Human
- Antigen symbol:RBM15
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:RNA binding mot protein 15|OTT1|SPEN|One twenty two protein|RBM15_HUMAN.|OTT
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Fusion Protein
- Purification:Protein A Purification
- Cat. no.:10093-394
- Supplier No.:66059-1-IG
Specifications
About this item
RNA-binding motif protein 15 (RBM15) belongs to the SPEN protein family, which have repressor function in several signaling pathway, and may bind to RNA through interaction with spliceosome components. It was first described as a 5′ translocation partner of the MAL gene in t(1,22)(p13;q13) infant acute megakaryocytic leukemia, and it functions in murine hematopoiesis through modulating Notch-induced transcriptional activation, which play crucial roles in leukemogenesis. Decreasing RBM15 levels with RNA interference could inhibit the growth and proliferation, block the cell cycle, and induce apoptosis in CML cells.
Western Blot: Hela Cells, 1:500-1:5000; IF: Hela Cells, 1:10-1:100; IP: HEK-293 Cells, 1:200-1:2000
Type: Primary
Antigen: RBM15
Clonality: Monoclonal
Clone: 4A1A4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human