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Specifications
- Antibody type:Primary
- Antigen name:RNA Binding Motif Protein 4
- Clonality:Monoclonal
- Clone:3H3F12
- Host:Mouse
- Isotype:IgG2a
- Reactivity:Human
- Antigen symbol:RBM4
- Conjugation:Unconjugated
- ELISA:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:ZCRB3A|RBM4A|LARK|ZCCHC21
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Protein A Purification
- Supplier No.:60292-1-IG
Specifications
About this item
RBM4, RNA-binding motif protein4, contains 2 RRM-type RNA-binding motif and a retroviral-type(RT) zinc finger. RNA-binding factor participates in number of aspects of cellular processes such as alternative splicing of pre-mRNA and translation regulation. RBM4 recruits eIF4A1 to stimulate IRES-dependent translation in responds to cellular stress. Once assembled at the rHRE, the HIF2A-RBM4-eIF4E2 complex captures the 5-prime cap and targets mRNAs to polysomes for active translation, thereby evading hypoxia-induced repression of protein synthesis.
Western Blot: HeLa Cells, 1:500-1:5000
Type: Primary
Antigen: RBM4
Clonality: Monoclonal
Clone: 3H3F12
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human