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Specifications
- Antibody type:Primary
- Antigen name:U2 Small Nuclear Rna Auxiliary Factor 1
- Clonality:Monoclonal
- Clone:2B7F11
- Host:Mouse
- Isotype:IgG2c
- Reactivity:Human
- Antigen symbol:U2AF1
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:RNU2AF1|RN|U2AFBP|U2AF35|FP793
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Protein A Purification
- Supplier No.:60289-1-IG
Specifications
About this item
U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.
Western Blot: HeLa Cells, 1:500-1:5000; IHC: Human breast cancer Tissue, 1:20-1:200
Type: Primary
Antigen: U2AF35
Clonality: Monoclonal
Clone: 2B7F11
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2c
Reactivity: Human