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Specifications
- Antibody type:Primary
- Antigen name:Chemokine (C-X-C motif) Ligand 16
- Clonality:Monoclonal
- Clone:2H7B3
- Host:Mouse
- Isotype:IgG2a
- Reactivity:Human,Mouse
- Antigen symbol:CXCL16
- Conjugation:Unconjugated
- ELISA:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:SR-PSOX|Zmynd15|SRPSOX|CXCLG16|CXCL16v2
- Storage buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Caprylic acid/ammonium sulfate precipitation
- Cat. no.:10085-422
- Supplier No.:60123-1-IG
Specifications
About this item
CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II–induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow–derived fibroblast accumulation.
Western Blot:SH-SY5Y Cells, 1:200-1:1000
Type: Primary
Antigen: CXCL16
Clonality: Monoclonal
Clone: 2H7B3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: