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Specifications
- Antibody type:Primary
- Antigen name:Melanoma Antigen Family D1
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:MAGED1
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:150 µL
- Western blot:Yes
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Fusion Protein
- Purification:Antigen affinity Purification
- Supplier No.:22053-1-AP
Specifications
About this item
MAGED1 (also known as NRAGE or Dlxin-1) is a member of the type II melanoma antigen (MAGE) family of protein. MAGED1 can interact with the nerve growth factor receptor p75NTR, antagonize the association of p75NTR with TrkA, inhibit cell cycle progression, and facilitate p75NTR-mediated apoptosis . It has been reported that MAGED1 binds Dlx5 and regulates its transcriptional function. In vivo, MAGED1 binds not only Dlx5 but also Dlx7 and Msx2 and forms homomultimers . MAGED1 knockout mice show depressive behavior and impairments of circadian rhythm . Three transcript variants encoding two different isoforms (86kDa and 92 kDa) have been found for the gene of MAGED1.
Western Blot:A549 Cells, 1:500-1:5000; IHC: Human Placenta Tissue, 1:20-1:200
Type: Primary
Antigen: MAGED1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat