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Specifications
- Antibody type:Primary
- Antigen name:Cyclin T1
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:CCNT1
- Conjugation:Unconjugated
- ELISA:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:CCNT|CycT1|CCNT1|CYCT1|Cyclin-T|HIVE1
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Peptide
- Purification:Antigen affinity Purification
- Cat. no.:10085-482
- Supplier No.:20992-1-AP
Specifications
About this item
CCNT1, also named as CycT1, belongs to the cyclin family and Cyclin C subfamily. It is a regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex which also called positive transcription elongation factor B (P-TEFb). In case of HIV or SIV infections, CCNT1 binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA). CCNT1 serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing transcription of viral genes. The antibody is specific to CCNT1.
Western Blot:K-562 Cells, 1:200-1:1000
Type: Primary
Antigen: CCNT1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat