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Specifications
- Antibody type:Primary
- Antigen name:Actinin alpha 4
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:ACTN4
- Conjugation:Unconjugated
- ELISA:Yes
- Flow cytometry:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:FSGS|F-actin cross-linking protein|Alpha-actinin-4|ACTININ-4|Non-muscle alpha-actinin 4|FSGS1
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Fusion Protein
- Purification:Antigen affinity Purification
- Supplier No.:19096-1-AP
Specifications
About this item
ACTN4 (alpha actinin 4) is a ubiquitous actin-binding protein that cross-links actin filaments into bundles to form filopodia, and has a crucial role in cytoskeletal organization. ACTN4 is colocalized with actin stress fibers and is dispersed in the cytoplasm and in the nucleus. Increased levels of ACTN4 have been associated with cancer metastasis, indicating its implication in cancer cell migration and metastasis. Defects in ACTN4 cause glomerular disease. This antibody recognizes 100-105 kDa of endogenous ACTN4 protein in various lysates. (22370640, 10700177)
Western Blot: HepG2 Cells, 1:500-1:5000; IHC: Human breast cancer Tissue, 1:20-1:200; IF: MCF-7 Cells, 1:10-1:100; IP: HeLa Cells, 1:500-1:5000; FC: HeLa Cells, N/A
Type: Primary
Antigen: ACTN4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat